BIOREACTOR

ZETA bioreactor systems are designed for animal cell culture and other biopharmaceutical processes that require precise control, sterility, and scalability. They provide the right environment for cell growth and are suitable for applications such as vaccine production, monoclonal antibody manufacturing, and other high-value bioprocesses.

Built for reliable operation and consistent process performance, our bioreactors support controlled cultivation, smooth transition to larger production volumes, and integration into modern pharmaceutical and biotech production environments.

Usage

Bioreactors are used in pharmaceutical, biotechnology, and research environments for cultivating mammalian cells under tightly controlled conditions. They support process development, scale-up, and commercial production of vaccines, monoclonal antibodies, recombinant proteins, and advanced therapies.

Cell Culture

Provides a controlled environment for mammalian cell culture and tissue growth, helping maintain the stable conditions needed for reliable bioprocess performance.

Process Control

Supports accurate control of temperature, pH, dissolved oxygen, nutrient supply, and other key process parameters to provide suitable conditions throughout cultivation.

 

Mixing

Ensures uniform distribution of nutrients, gases, and cells within the vessel, helping improve process consistency and promote efficient biological activity.

Aeration

Enables effective oxygen transfer and carbon dioxide removal to enable aerobic cell culture processes and maintain optimal growth conditions.

Automation

Allows real-time monitoring and control of key process variables. The system can be integrated with automation platforms such as Siemens PCS7 / TIA Portal for consistent and repeatable operation.

Scale-up

Supports the transition from laboratory and pilot-scale development to larger production volumes while maintaining similar process conditions and performance.

Product Recovery

Supports efficient recovery of products such as proteins or metabolites as part of a broader bioprocess workflow, including downstream processing requirements.

Sterilisation

Maintains aseptic operating conditions through integrated Clean-in-Place (CIP) and Sterilise-in-Place (SIP) capabilities, helping prevent contamination and ensure regulatory compliance.

Bioreactor Applications

Vaccine Production

Supports scalable cultivation processes for viral vector and vaccine manufacturing.

Monoclonal Antibody Production

Enables high-yield mammalian cell culture for mAb manufacturing.

Biopharmaceutical Process Development

Supports process optimisation, technology transfer, and production readiness.

Commercial Bioprocessing

Delivers reliable, GMP-compliant production at commercial scale.

 

Process Capabilities

Supports batch, fed-batch, and perfusion process capabilities

How the System Supports the Process

ZETA bioreactor systems are designed to support controlled cultivation from early-stage development through larger-scale production. By combining vessel design, process control, mixing, aeration, and automation, the system helps create the conditions required for efficient and repeatable biological performance.

1. Controlled cultivation

The system provides suitable conditions for cell growth through precise control of temperature, pH, oxygen, and nutrient conditions.

2. Real-time monitoring

Critical process parameters can be monitored and adjusted throughout cultivation to maintain consistency and reduce process deviation.

3. Scalable operation

The system supports process development and progression to larger production volumes, helping teams move from smaller trials to larger production volumes more smoothly.

4. Integration into broader workflows

Bioreactors can be aligned with downstream operations and automation systems to support efficient overall bioprocess execution.

Case Study: How We Scale Up Bioreactor Design from Lab to GMP Facility

Frequently Asked Questions FAQ

What is a bioreactor used for?

A bioreactor is used to cultivate cells, tissues, or microorganisms under defined operating conditions for pharmaceutical, biotechnology, and research applications.

Which industries can use bioreactor systems?

Bioreactor systems are suitable for pharmaceutical, biotechnology, healthcare, and research environments where precise biological processes are required.

Can the system support scale-up?

Yes. The system is designed to support scale-up from smaller process development stages to larger production requirements while maintaining consistent operating conditions.

What process parameters can be controlled?

Typical controlled parameters include temperature, pH, oxygen levels, nutrient supply, and dissolved oxygen, helping provide suitable conditions for cell growth and process performance.

Can the system be integrated with automation platforms?

Yes. ZETA bioreactor systems can be integrated with automation platforms such as Siemens PCS7 / TIA Portal for process automation and monitoring.

What capacity range is available?

The current capacity range is 5 L to 12 KL.

Why choose ZETA Bioreactor Systems

ZETA bioreactor systems are developed for pharmaceutical and biotech environments where control, consistency, and operational performance are essential. They are built to meet demanding cultivation requirements while giving teams the flexibility to scale processes and maintain high standards of operation.

Key advantages include:

  • controlled process conditions
  • reliable mixing and aeration
  • automation-ready integration
  • scalable capacity range
  • suitability for regulated biopharma environments

Let’s Solve Your Biomanufacturing Challenges Together

From process development to GMP-compliant production, we deliver science-driven solutions tailored to your operational needs.

We use your data exclusively in accordance with our Privacy Policy